It contains over 8,000 square feet of class 100 and class 1000 clean room laboratory and … of one’s self or others É Abusing laboratory equipment É Operating laboratory equipment … Table of Contents PREFACE ….. 1 GENERAL POLICIES AND PROCEDURES Building access and circulation procedures …..2 Personnel Access …..

Laser Installations: Lasers produce non-ionizing radiation capable of causing eye injury. Lasers operating outside of the visible light region (UV or IR) axe especially hazardous. Laser dyes are complex fluorescent organic compounds. In solution with organic solvents, these dyes form a lasing medium. Toxicity information on commercially available laser dyes is not extensive. However, the current research has found a number of the dyes to be mutagenic and possibly carcinogenic. The active dyes identified thus far include: Cresyl Violet 670 Perchlorate Coumarin 7 Coumarin 102 Coumarin 535 DcM DODU LD 490 Nile Blue 690 Perchlorate N,N,NN’-Tetraethyldiami noterphenyl
Special laboratory hazards There are several groups of chemicals that present severe hazards even for the small quantities used in most laboratories. For safe operations, these substances require special handling techniques or equipment. Some of them also have specific storage and shipping requirements. Oxygen and Moisture Sensitive Compounds: Many chemical compounds deteriorate when exposed to air. For most of these, oxidation only causes a decrease in purity. But for a few, extreme reactivity with oxygen leads to other effects. Another group of compounds reacts with atmospheric moisture and causes the release of toxic or flammable gases or vapors or the generation of enough heat to cause fires and explosions. EXAMPLES: Compound Effects Aluminum Alkyls React with moisture to generate extremely flammable hydrocarbon vapor. Dichlorosilane Forms silicon dioxide and hydrogen chloride on contract with air. Will detonate spontaneously under some conditions. Phosphides React with moisture to form highly toxic phosphine (TLV = 0.3 ppm.) Potassium Reacts with moisture to release hydrogen and with oxygen to cause ignition and explosion. Selenides Moisture causes release of the extremely toxic hydrogen selenide (TLV = 0.05 ppm.) Sodium Reacts with moisture to release hydrogen. The heat generated may cause a fire. Sulfides Hydrogen sulfide (TLV = 10 ppm.) formed on contact with moist air. Policies and Procedures Handbook Pag e 21
Page 22 Policies and Procedures Handbook Material Safety Data Sheets (MSDS) The MSDS should be the first source of information about the hazards associated with a chemical. Typically, an MSDS will contain the following information, usually in separate sections on the sheet: É name, address, and phone number of manufacturer É chemical name, synonyms, and Chemical Abstracts (CAS) Number É physical properties É a listing of hazardous constituents for mixtures É health hazard information É first-aid measures É fire fighting measures É handling and storage precautions É exposure controls/personal protection É stability and reactivity Newer MSDSs will contain the following additional information: É toxicological information É ecological information É disposal considerations É transport information É regulatory information É other information Manufacturers are required to provide a MSDS for each chemical product sold. The Division of Environmental Health and Safety (DEHS) maintains a repository of all the MSDSs received by the campus. If DEHS does not have a MSDS for a product you are using, DEHS will obtain one. Government regulations specify that MSDSs be readily available to employees. DEHS recommends that each unit obtain hard copies of MSDSs for the products most commonly used…..

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